Silencing Synapses with DREADDs
نویسندگان
چکیده
In this issue of Neuron, Stachniak et al. (2014) determine that the chemogenetic silencer hM4Di-DREADD suppresses presynaptic glutamate release, and by generating an axon-targeted hM4Di variant they demonstrate that it can be used to locally silence synaptic transmission in neural circuits.
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عنوان ژورنال:
- Neuron
دوره 82 شماره
صفحات -
تاریخ انتشار 2014